An extract from grape seeds can destroy cancer cells, US research suggests.
In lab experiments, scientists found that the extract stimulated leukaemia cells to commit suicide.
Within 24 hours, 76% of leukaemia cells exposed to the extract were killed off, while healthy cells were unharmed, Clinical Cancer Research reports.
The study raises the possibility of new cancer treatments, but scientists said it was too early to recommend that people eat grapes to ward off cancer.
Grape seeds contain a number of antioxidants, including resveratrol, which is known to have anti-cancer properties, as well as positive effect on the heart.
Previous research has shown grapeseed extract has an effect on skin, breast, bowel, lung, stomach and prostate cancer cells in the laboratory.
It can also reduce the size of breast tumours in rats and skin tumours in mice.
However, the University of Kentucky study is the first to test its impact on a blood cancer.
Lead researcher Professor Xianglin Shi said: "These results could have implications for the incorporation of agents such as grapeseed extract into prevention or treatment of haematological (blood) malignancies and possibly other cancers.
"What everyone seeks is an agent that has an effect on cancer cells but leaves normal cells alone, and this shows that grapeseed extract fits into this category."
The researchers exposed leukaemia cells to grape extract in a range of different doses.
Apoptosis
One of the higher doses produced a marked effect, causing large numbers of the cells to commit suicide in a process known as apoptosis.
This is a natural method of getting rid of damaged and potentially dangerous cells.
When the mechanism behind apoptosis breaks down, cancerous cells can survive and multiply.
The researchers found grapeseed extract activates a protein called JNK which helps to regulate apoptosis.
When they exposed the leukaemia cells to an agent that inhibits JNK, the grapeseed extract effect was cancelled out.
Silencing the gene that makes JNK also blocked the extract's ability to kill cancer cells.
Kat Arney, Cancer Research UK's senior cancer information officer, warned against jumping to firm conclusions.
She said: "This is yet another story highlighting the potential cancer-fighting properties of naturally-occurring chemicals.
"Although interesting, it's still a long way from being a treatment that we can give to patients."
http://news.bbc.co.uk/2/hi/health/7803619.stm
Wednesday, December 31, 2008
Wednesday, October 22, 2008
The Secret To Great Health Revealed
Q: What is the secret to Great Health?
A: Olive Oil on your food and skin, drinking port wine, and eating 2 pounds of chocolate a week!
Jeanne Louise Calment from Arles, France
122 years and 164 days old
(Feb. 21, 1875 - Aug. 4, 1997)
Guinness Book of Records as the "Oldest Person Who Had Ever Lived"
Calment's remarkable health presaged her later record. At age 85, she took up fencing, and at 100, she was still riding a bicycle. Jeanne lived on her own until shortly before her 110th birthday, when it was decided that she needed to be moved to a nursing home. However, Jeanne was still in good shape, and was able to walk until a fall at age 114 years and 11 months, which required surgery.
She reportedly attributed her longevity and relatively youthful appearance for her age to olive oil, which she said she poured on all her food and rubbed onto her skin, as well as a diet of port wine, and nearly 2 pounds of chocolate eaten every week.
http://en.wikipedia.org/wiki/Jeanne_Calment
A: Olive Oil on your food and skin, drinking port wine, and eating 2 pounds of chocolate a week!
Jeanne Louise Calment from Arles, France
122 years and 164 days old
(Feb. 21, 1875 - Aug. 4, 1997)
Guinness Book of Records as the "Oldest Person Who Had Ever Lived"
Calment's remarkable health presaged her later record. At age 85, she took up fencing, and at 100, she was still riding a bicycle. Jeanne lived on her own until shortly before her 110th birthday, when it was decided that she needed to be moved to a nursing home. However, Jeanne was still in good shape, and was able to walk until a fall at age 114 years and 11 months, which required surgery.
She reportedly attributed her longevity and relatively youthful appearance for her age to olive oil, which she said she poured on all her food and rubbed onto her skin, as well as a diet of port wine, and nearly 2 pounds of chocolate eaten every week.
http://en.wikipedia.org/wiki/Jeanne_Calment
Monday, October 13, 2008
French Paradox
The French paradox refers to the observation that the French suffer a relatively low incidence of coronary heart disease, despite having a diet relatively rich in saturated fats. The phenomenon was first noted by Irish physician Samuel Black in 1819. The term French paradox was coined by Dr. Serge Renaud, a scientist from Bordeaux University in France in 1992. When a description of this paradox was aired in the United States on 60 Minutes in 1991 with the proposal that red wine, or alcohol, decreases the incidence of cardiac diseases, the consumption of red wine increased 44% and some wineries began lobbying for the right to label their products "health food".
However, some health researchers question the validity of this paradox. Statistics collected by the WHO from 1990-2000 show that the incidence of heart disease in France may have been underestimated, and may in fact be similar to that of neighboring countries. In 2008 it was found that high doses of resveratrol (a constituent of red wine) mimicked the benefits of caloric restriction (extended lifespan and reduced effects of aging) in a mice study.
According to FAO data, the average French person consumed 108 grams per day of fat from animal sources in 2002 while the average American consumed only 72. The French eat four times as much butter, 60 percent more cheese and nearly three times as much pork. Although the French consume only slightly more total fat (171 g/d vs 157 g/d), they consume much more saturated fat because Americans consume a much larger proportion of fat in the form of vegetable oil, with most of that being soybean oil. However, according to data from the British Heart foundation, in 1999, rates of death from coronary heart disease among males aged 35–74 years was 115 per 100,000 people in the US but only 83 per 100,000 in France.
It has been suggested that France's high red wine consumption is a primary factor in the trend. This theory was expounded in a 60 Minutes broadcast in 1991. The program catalysed a large increase in North American demand for red wines from around the world. It is believed that one of the ingredients in red wine potentially related to this effect is resveratrol.
http://en.wikipedia.org/wiki/French_paradox
However, some health researchers question the validity of this paradox. Statistics collected by the WHO from 1990-2000 show that the incidence of heart disease in France may have been underestimated, and may in fact be similar to that of neighboring countries. In 2008 it was found that high doses of resveratrol (a constituent of red wine) mimicked the benefits of caloric restriction (extended lifespan and reduced effects of aging) in a mice study.
According to FAO data, the average French person consumed 108 grams per day of fat from animal sources in 2002 while the average American consumed only 72. The French eat four times as much butter, 60 percent more cheese and nearly three times as much pork. Although the French consume only slightly more total fat (171 g/d vs 157 g/d), they consume much more saturated fat because Americans consume a much larger proportion of fat in the form of vegetable oil, with most of that being soybean oil. However, according to data from the British Heart foundation, in 1999, rates of death from coronary heart disease among males aged 35–74 years was 115 per 100,000 people in the US but only 83 per 100,000 in France.
It has been suggested that France's high red wine consumption is a primary factor in the trend. This theory was expounded in a 60 Minutes broadcast in 1991. The program catalysed a large increase in North American demand for red wines from around the world. It is believed that one of the ingredients in red wine potentially related to this effect is resveratrol.
http://en.wikipedia.org/wiki/French_paradox
Wednesday, October 8, 2008
Vino Q & A
Q & A (part 1):
1. How many acres are planted to grapes worldwide?
2. Among the world's fruit crops, where do wine grapes rank in number of acres planted?
3. How many countries import California wines?
4. What was the primary fruit crop in Napa Valley during the 1940's?
5. How many gallons of wine were lost in the 1906 San Francisco earthquake?
6. When was phylloxera first discovered in California?
7. How many acres of Napa County vineyards have been replanted in the last 15 years because of phylloxera?
8. How many more acres of Napa County vineyards will need replacement?
9. How long does it take to harvest a commercial crop from newly replanted grape vines?
10. How many varieties of wine grapes exist worldwide?
11. How much does it cost per bottle to age wine in a French oak barrel?
12. How much does it cost per bottle to age wine in only new French oak barrels?
13. How much white zinfandel is consumed in this country?
Answers:
1) 20 million
2) #1
3) 164
4) Prunes
5) 30 million
6) August 19, 1873
7) 10,450
8) 4,450
9) 4-5 years
10) 10,000
11) 90 cents
12) $2.50
13) Too much!
Q & A (part 2):
1. When was the first known reference to a specific wine vintage?
2. How old was the wine being “reviewed”?
3. A bottle of opened wine stored in the refrigerator lasts how much longer than it would if stored at room temp?
4. How many oak species are there?
5. How many are used in making oak barrels?
6. What percent of an oak tree is suitable for making high grade wine barrels?
7. The 1996 grape crop in Napa Valley was down what percentage from normal?
8. What are the top three U.S. states in terms of wine consumption?
9. What percentage of legal-aged Americans contacted in a Nielson phone survey drink wine?
10. What percentage of restaurant wine sales do red wines represent?
11. What is the average cost of the grapes used to produce a $20 bottle of wine?
Answers:
1. Roman Historian Pliny the Elder rated 121 B.C. as a vintage “of the highest excellence.”
2. 200 years old! Pliny the Elder wrote the history of the Roman Empire around 70 A.D.
3. 6-16 times longer
4. 400
5. 20
6. 5%
7. 20-25%
8. CA, NY, FL
9. 58%
10. 55%
11. $2.64
1. How many acres are planted to grapes worldwide?
2. Among the world's fruit crops, where do wine grapes rank in number of acres planted?
3. How many countries import California wines?
4. What was the primary fruit crop in Napa Valley during the 1940's?
5. How many gallons of wine were lost in the 1906 San Francisco earthquake?
6. When was phylloxera first discovered in California?
7. How many acres of Napa County vineyards have been replanted in the last 15 years because of phylloxera?
8. How many more acres of Napa County vineyards will need replacement?
9. How long does it take to harvest a commercial crop from newly replanted grape vines?
10. How many varieties of wine grapes exist worldwide?
11. How much does it cost per bottle to age wine in a French oak barrel?
12. How much does it cost per bottle to age wine in only new French oak barrels?
13. How much white zinfandel is consumed in this country?
Answers:
1) 20 million
2) #1
3) 164
4) Prunes
5) 30 million
6) August 19, 1873
7) 10,450
8) 4,450
9) 4-5 years
10) 10,000
11) 90 cents
12) $2.50
13) Too much!
Q & A (part 2):
1. When was the first known reference to a specific wine vintage?
2. How old was the wine being “reviewed”?
3. A bottle of opened wine stored in the refrigerator lasts how much longer than it would if stored at room temp?
4. How many oak species are there?
5. How many are used in making oak barrels?
6. What percent of an oak tree is suitable for making high grade wine barrels?
7. The 1996 grape crop in Napa Valley was down what percentage from normal?
8. What are the top three U.S. states in terms of wine consumption?
9. What percentage of legal-aged Americans contacted in a Nielson phone survey drink wine?
10. What percentage of restaurant wine sales do red wines represent?
11. What is the average cost of the grapes used to produce a $20 bottle of wine?
Answers:
1. Roman Historian Pliny the Elder rated 121 B.C. as a vintage “of the highest excellence.”
2. 200 years old! Pliny the Elder wrote the history of the Roman Empire around 70 A.D.
3. 6-16 times longer
4. 400
5. 20
6. 5%
7. 20-25%
8. CA, NY, FL
9. 58%
10. 55%
11. $2.64
Monday, October 6, 2008
6 Reasons Why a Little Glass of Wine Each Day May Do You Good
The list of wine’s benefits is long—and getting more surprising all the time. Already well-known as heart-healthy, wine in moderation might help you lose weight, reduce forgetfulness, boost your immunity, and help prevent bone loss.
With America likely to edge out France and Italy in total wine consumption in the near future, according to one analyst, and with women buying more than 6 out of every 10 bottles sold in this country, we’re happy to report that wine may do all of the following:
1. Feed your head. Wine could preserve your memory. When researchers gave memory quizzes to women in their 70s, those who drank one drink or more every day scored much better than those who drank less or not at all. Wine helps prevent clots and reduce blood vessel inflammation, both of which have been linked to cognitive decline, as well as heart disease, explains Tedd Goldfinger, DO, of University of Arizona School of Medicine. Alcohol also seems to raise HDL, the good cholesterol, which helps unclog your arteries.
2. Keep the scale in your corner. Studies find that people who drink wine daily have lower body mass than those who indulge occasionally; moderate wine drinkers have narrower waists and less abdominal fat than people who drink liquor. Alcohol may encourage your body to burn extra calories for as long as 90 minutes after you down a glass. Beer seems to have a similar effect.
3. Boost your body’s defenses. In one British study, those who drank roughly a glass of wine a day reduced by 11 percent their risk of infection by Helicobacter pylori bacteria, a major cause of gastritis, ulcers, and stomach cancers. As little as half a glass may also guard against food poisoning caused by germs like salmonella when people are exposed to contaminated food, according to a Spanish study.
4. Guard against ovarian woes. When Australian researchers recently compared women with ovarian cancer and cancer-free women, they found that roughly one glass of wine a day seemed to reduce the risk of the disease by as much as 50 percent. Earlier research at the University of Hawaii produced similar findings. Experts suspect this may be due to antioxidants or phytoestrogens, which have high anticancer properties, in the wine. And in a recent University of Michigan study, a red wine compound helped kill ovarian cancer cells in a test tube.
5. Build better bones. On average, women who drink moderately seem to have higher bone mass than abstainers. Alcohol appears to boost estrogen levels; the hormone seems to slow the body’s destruction of old bone more than it slows the production of new bone.
6. Prevent blood-sugar trouble. Premenopausal women who drink one or two glasses of wine a day are 40 percent less likely than women who don’t drink to develop type 2 diabetes, according to a 10-year study by Harvard Medical School. While the reasons aren’t clear, wine seems to reduce insulin resistance in diabetic patients.
Visit Healthy Wine Life to find out how you can make Your Health Better Today!
http://www.wineshopathome.com/HealthyWineLife
With America likely to edge out France and Italy in total wine consumption in the near future, according to one analyst, and with women buying more than 6 out of every 10 bottles sold in this country, we’re happy to report that wine may do all of the following:
1. Feed your head. Wine could preserve your memory. When researchers gave memory quizzes to women in their 70s, those who drank one drink or more every day scored much better than those who drank less or not at all. Wine helps prevent clots and reduce blood vessel inflammation, both of which have been linked to cognitive decline, as well as heart disease, explains Tedd Goldfinger, DO, of University of Arizona School of Medicine. Alcohol also seems to raise HDL, the good cholesterol, which helps unclog your arteries.
2. Keep the scale in your corner. Studies find that people who drink wine daily have lower body mass than those who indulge occasionally; moderate wine drinkers have narrower waists and less abdominal fat than people who drink liquor. Alcohol may encourage your body to burn extra calories for as long as 90 minutes after you down a glass. Beer seems to have a similar effect.
3. Boost your body’s defenses. In one British study, those who drank roughly a glass of wine a day reduced by 11 percent their risk of infection by Helicobacter pylori bacteria, a major cause of gastritis, ulcers, and stomach cancers. As little as half a glass may also guard against food poisoning caused by germs like salmonella when people are exposed to contaminated food, according to a Spanish study.
4. Guard against ovarian woes. When Australian researchers recently compared women with ovarian cancer and cancer-free women, they found that roughly one glass of wine a day seemed to reduce the risk of the disease by as much as 50 percent. Earlier research at the University of Hawaii produced similar findings. Experts suspect this may be due to antioxidants or phytoestrogens, which have high anticancer properties, in the wine. And in a recent University of Michigan study, a red wine compound helped kill ovarian cancer cells in a test tube.
5. Build better bones. On average, women who drink moderately seem to have higher bone mass than abstainers. Alcohol appears to boost estrogen levels; the hormone seems to slow the body’s destruction of old bone more than it slows the production of new bone.
6. Prevent blood-sugar trouble. Premenopausal women who drink one or two glasses of wine a day are 40 percent less likely than women who don’t drink to develop type 2 diabetes, according to a 10-year study by Harvard Medical School. While the reasons aren’t clear, wine seems to reduce insulin resistance in diabetic patients.
Visit Healthy Wine Life to find out how you can make Your Health Better Today!
http://www.wineshopathome.com/HealthyWineLife
Health Benefits in Drinking Wine
Drinking wine has several advantages today other than its great taste. Several studies have shown that drinking wine can also be very healthy for you.
Scientific research on the health benefits of drinking wine has been extensive over the past decade. These studies suggest a number of positive effects that drinking wine can have on your health. Researchers have shown that drinking wine, in moderation, can help reduce the risk of heart disease. Studies show it keeps your heart beating in a more healthy rhythm. Researchers found that women in particular with heart disease who drank wine had an increase in heart rate variability, which is a marker of the changes in time intervals between heartbeats. It is known that a decrease in the heart rate variability has been linked to a higher risk of heart disease that can lead to death.
Researchers say that wine increases your HDL (good cholesterol) levels thus decreasing the risk of heart disease. This along with the effect the heart rate variability may be one more reason why drinking wine reduces the risk of heart disease and heart-related deaths.
Wine has also been found to affect favorably the body's adsorption of antioxidants in food and helps metabolize fat more efficiently. A study done in the journal "Heart", studied 102 women under the age 75 who survived a heart attack or heart surgery to clear blocked arteries. During their recovery period, the participants were asked to chronicle how much and what kind of alcohol they consumed.
One year later, researchers used a heart monitor to measure the women's heart activity over a 24-hour period as they went through their normal daily activities. The study showed that heart rate variability was the highest among women who drank at least half a glass of wine per day and lowest among women who drank no alcohol at all. As the studies show, drinking wine can definitely be a health benefit.
Additional Health Benefits in Drinking Red Wine
Studies show drinking red wine in particular may have additional benefits on your health. Researches show red wine can decrease the risk of coronary heart disease, lung and prostate cancers, dementia, stroke, diabetes, macular degeneration, kidney stones and osteoporosis. A recent Spanish study even implies drinking red wine may even help fight off the common cold.
For optimal health benefits, drink small amounts of wine daily as part of a meal.
Remember as in all things, drinking in moderation is always the healthiest.
So go ahead and savor the taste of drinking wine while enjoying the health benefits it can have on your life!
http://www.wineshopathome.com/HealthyWineLife
Scientific research on the health benefits of drinking wine has been extensive over the past decade. These studies suggest a number of positive effects that drinking wine can have on your health. Researchers have shown that drinking wine, in moderation, can help reduce the risk of heart disease. Studies show it keeps your heart beating in a more healthy rhythm. Researchers found that women in particular with heart disease who drank wine had an increase in heart rate variability, which is a marker of the changes in time intervals between heartbeats. It is known that a decrease in the heart rate variability has been linked to a higher risk of heart disease that can lead to death.
Researchers say that wine increases your HDL (good cholesterol) levels thus decreasing the risk of heart disease. This along with the effect the heart rate variability may be one more reason why drinking wine reduces the risk of heart disease and heart-related deaths.
Wine has also been found to affect favorably the body's adsorption of antioxidants in food and helps metabolize fat more efficiently. A study done in the journal "Heart", studied 102 women under the age 75 who survived a heart attack or heart surgery to clear blocked arteries. During their recovery period, the participants were asked to chronicle how much and what kind of alcohol they consumed.
One year later, researchers used a heart monitor to measure the women's heart activity over a 24-hour period as they went through their normal daily activities. The study showed that heart rate variability was the highest among women who drank at least half a glass of wine per day and lowest among women who drank no alcohol at all. As the studies show, drinking wine can definitely be a health benefit.
Additional Health Benefits in Drinking Red Wine
Studies show drinking red wine in particular may have additional benefits on your health. Researches show red wine can decrease the risk of coronary heart disease, lung and prostate cancers, dementia, stroke, diabetes, macular degeneration, kidney stones and osteoporosis. A recent Spanish study even implies drinking red wine may even help fight off the common cold.
For optimal health benefits, drink small amounts of wine daily as part of a meal.
Remember as in all things, drinking in moderation is always the healthiest.
So go ahead and savor the taste of drinking wine while enjoying the health benefits it can have on your life!
http://www.wineshopathome.com/HealthyWineLife
Healthy Wine Life
Benvenuto!
Welcome to the convenient and affordable way to taste and purchase delicious artisan wines. Great wines at great prices delivered right to your door. If you'd like to host an enjoyable, relaxed tasting in your home for your family and friends and get the chance to try great wines before you buy, contact Rocco today
HealthyWineLife@gmail.com
Planning an in-home tasting is simple and easy! It's a great way to get together with family and friends, or to liven up any social occasion. The tastings are so exciting, my calendar books up fast. So call or email today and let's get started! In the meantime, check out my site at http://www.wineshopathome.com/healthywinelife and sign up for my wine e-newsletter. You'll get the latest info on which wines are available and how to make the most of your wine lifestyle.
It's a great way to live a Healthy Life!
www.WineShopAtHome.com/HealthyWineLife
Ciao!
~ Rocco
HealthyWineLife@gmail.com
Welcome to the convenient and affordable way to taste and purchase delicious artisan wines. Great wines at great prices delivered right to your door. If you'd like to host an enjoyable, relaxed tasting in your home for your family and friends and get the chance to try great wines before you buy, contact Rocco today
HealthyWineLife@gmail.com
Planning an in-home tasting is simple and easy! It's a great way to get together with family and friends, or to liven up any social occasion. The tastings are so exciting, my calendar books up fast. So call or email today and let's get started! In the meantime, check out my site at http://www.wineshopathome.com/healthywinelife and sign up for my wine e-newsletter. You'll get the latest info on which wines are available and how to make the most of your wine lifestyle.
It's a great way to live a Healthy Life!
www.WineShopAtHome.com/HealthyWineLife
Ciao!
~ Rocco
HealthyWineLife@gmail.com
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